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        Dr  Sampurna Roy  MD

 

 
  Gastrointestinal Stromal Tumour

          

http://www.histopathology-india.net/Infection.htm

                

Omsk hemorrhagic fever virus (OHFV), is the only known tick-borne flavivirus to cause hemorrhagic disease in humans in the absence of encephalitis.

Omsk hemorrhagic fever (OHF) resembles Crimean fever and was first described in the Asiatic USSR (1947).

Endemic to the forested steppe-lake region of western Siberia, its animal reservoir is principally rodents.

Infections in humans come from the bites of infected ticks or from  contact with muskrats killed by hunters, in which case the muskrats were bitten by ticks infested with the virus from small rodents.

OHFV can be transmitted through the milk of infected goats or sheep  and isolated from aquatic animals and water.

Symptoms of OHF includes fever, headache, severe muscle pain, cough, dehydration, gastrointestinal symptoms and bleeding problems.

After 1-2 weeks of symptoms, some patients recover without complication.

In most patients in the beginning of the third week the symptoms    include fever and signs of encephalitis.

The diagnosis is made by virus isolation from blood or by serologic testing using enzyme-linked immunosorbent serologic assay (ELISA).

                   

Abstracts:

Structure of the envelope protein domain III of Omsk hemorrhagic fever virus.Virology. 2006 Jul 20;351(1):188-95. Epub 2006 May 2.

Molecular determinants of antigenicity of two subtypes of the tick-borne flavivirus Omsk haemorrhagic fever virus.J Gen Virol. 2004 Jun;85(Pt 6):1619-24.

Analysis of the complete genome of the tick-borne flavivirus Omsk hemorrhagic fever virus.Virology. 2003 Aug 15;313(1):81-90

Omsk hemorrhagic fever--current status of the problem.Vopr Virusol. 2000 May-Jun;45(3):4-9.

The clinico-epidemiological characteristics of Omsk hemorrhagic fever in 1988-1992.Zh Mikrobiol Epidemiol Immunobiol. 1995 Jul-Aug;(4):88-91

                 

 
 June  2009
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