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Pathology of Pulmonary Pleomorphic Undifferentiated Sarcoma (Malignant Fibrous Histiocytoma)

Dr Sampurna Roy MD     

 

Fibrous and and fibrohistiocytic tumours may present with symptoms of bronchial obstruction.

The so-called malignant fibrous histiocytoma is histologically characterized by cellular atypia, nuclear pleomorphism, bizarre mitotic figures.

There is lack of immunoreactivity for any of the specific tumour markers.

According to some authors the tumour basically represent diagnosis of exclusion.

Differential diagnosis:  Poorly differentiated variants of other sarcomas ; metastatic melanoma ; sarcomatoid (spindle cell and pleomorphic carcinoma).

Further reading

Primary pulmonary malignant fibrous histiocytoma.

Inflammatory malignant fibrous histiocytoma of the lung combined with fungal infection.

Successful management of a recurrent primary malignant fibrous histiocytoma of the lung: report of a case.

Malignant fibrous histiocytoma of the lung.

Primary malignant myxoid fibrous histiocytoma of the lung. Light and ultrastructural examination with review of the literature.

Malignant fibrous histiocytoma of the lung.

Primary malignant fibrous histiocytoma of the lung. A clinicopathologic and ultrastructural study of five cases.

Pulmonary malignant fibrous histiocytoma. Light and electron microscopic studies of one case.

Malignant fibrous histiocytoma of the lung.

Primary malignant fibrous histiocytoma of the lung. Fine needle aspiration cytologic features.

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

 

 


 

 

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