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Pathology of Glomus Tumour of the Lung

Dr Sampurna Roy MD  

 

Glomus is thought to derive from Sucquet-Hoyer canal (glomus apparatus), specialized arteriovenous anastomosis involved in blood and temperature control of skin.

Glomus apparatus have not been demonstrated in lung but  glomangioma has been reported in lung.

It is composed of round to polygonal cells arranged around cavernous blood spaces.

Surgical excision is curative.

Primary malignant glomus tumors of the lung are extremely rare.

Histological examination revealed a sheet-like proliferation of epithelioid glomus cells and fascicles of spindle cells.

The presence of increased mitotic activity, tumor necrosis and prominent intravascular invasion suggested malignancy.

The tumor cells were immunoreactive for vimentin, calponin, h-caldesmon, and alpha-smooth muscle actin, which indicated definitive smooth muscle differentiation.

Visit: Glomus Tumour of the Soft Tissue

 

Further reading:

A primary pulmonary glomus tumor complicated with hyperpyrexia and anemia.

Pulmonary glomus tumour: a case initially diagnosed as carcinoid tumour.

Primary pulmonary glomus tumor with contiguous spread to a peribronchial lymph node.

A primary pulmonary glomus tumor: a case report and review of the literature.

Primary pulmonary glomangioma: a coin lesion negative on PET study. Case report and literature review.

Glomus tumour of the lung: case report and literature review.

Pulmonary glomus tumor.

Malignant glomus tumor of the lung with multiple metastasis: a rare case report.

Pulmonary and mediastinal glomus tumors--report of five cases including a pulmonary glomangiosarcoma: a clinicopathologic study with literature review.

Primary pulmonary glomus tumor: a clinicopathologic and immunohistochemical study of two cases.

Glomangioma of the lung.

Glomangioma of the lungs: a rare differential diagnosis of a pulmonary tumour.

A vascular lesion with smooth muscle differentiation presenting as a coin lesion in the lung: glomus tumor versus hemangiopericytoma.

 

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)

 

 


 

 

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