Mucous and serous
glands in the respiratory tract rarely produce tumours that
are histologically identical to tumours derived from the salivary glands
of the head and neck.
Electron microscopic and immunohistochemical studies confirm the similarity between tumours in these two locations.
Primary lung cancers, histologically resembling salivary gland carcinoma, usually arise from submucosal glands of the bronchi and most of these tumours are mucoepidermoid carcinomas, adenoid cystic carcinomas, and mixed tumours.
They may arise within pulmonary parenchyma in the periphery of the lung without direct connection to the bronchial structure.
These tumours can occur at any age without sex predilection, and at any lung or lung segment.
Their clinical manifestations are similar to the lung cancers.
They behave as low-grade cancer with good prognosis when completely excised.But poorly differentiated tumors are highly aggressive leading to death due to widespread metastases.
Different histologic patterns observed in lungs are as follows:
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