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Endocrine Pathology Online

Pathology of Riedel's Thyroiditis

 Dr Sampurna Roy MD    




Riedel's thyroiditis is a rare chronic inflammatory disease of the thyroid first recognized by Bernhard Riedel in 1893.

This can mimic carcinoma  both clinically and pathologically.

The fibrotic process leads to a very firm thyroid adherent to adjacent structures.

Histopathology shows a lymphocytic infiltrate, follicular destruction (except that Hurthle cells are rare), and diffuse reticular


This may extend into adjacent muscle.

Obliterative changes may be seen in veins passing through the process.

The plasma cells in the infiltrate express IgA.

Lymphoid aggregates are uncommon.

Riedelís thyroiditis is associated with other fibromatoses and is probably distinct from fibrous variant Hashimoto's

thyroiditis, occurring in a different group of patients with a different profile of HLA types.

The differential diagnosis is against carcinomas, especially the cellular variant of anaplastic carcinoma and medullary



Further reading:

Could Riedel's thyroiditis be subacute thyroiditis? A case report.

Riedel's thyroiditis in a patient with recurrent subacute thyroiditis: a case report and review of the literature.

A case of Riedel's thyroiditis.

Riedel's thyroiditis. Personal experience.

Riedel's thyroiditis with increased IgG4 plasma cells: evidence for an underlying IgG4-related sclerosing disease?

Case of concurrent Riedel's thyroiditis, acute suppurative thyroiditis, and micropapillary carcinoma.

Clinical and pathological features of Riedel's thyroiditis.

Riedel's thyroiditis in a patient with recurrent subacute thyroiditis: a case report and review of the literature.

Riedel's thyroiditis: impact and strategy of a challenging surgery.

Differential diagnosis and management of airway obstruction in Riedel's thyroiditis: a case report.

Riedel's thyroiditis.

Riedel's thyroiditis: an autoimmune or primary fibrotic disease?

Riedel's thyroiditis: clinical, pathological and imaging features.

Fine-needle aspiration of Riedel's disease: report of a case and review of the literature.

An unusual form of Riedel's thyroiditis: a case report and review of the literature.



Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)






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