Endocrine Pathology Online
Pathology of Riedel's Thyroiditis
Riedel's thyroiditis is a rare chronic inflammatory disease of the
thyroid first recognized by Bernhard Riedel in 1893.
This can mimic carcinoma both clinically and pathologically.
The fibrotic process leads to a very firm thyroid adherent to adjacent structures.
Histopathology shows a lymphocytic infiltrate, follicular destruction (except that Hurthle cells are rare), and diffuse reticular
This may extend into adjacent muscle.
Obliterative changes may be seen in veins passing through the process.
The plasma cells in the infiltrate express IgA.
Lymphoid aggregates are uncommon.
Riedelís thyroiditis is associated with other fibromatoses and is probably distinct from fibrous variant Hashimoto's
thyroiditis, occurring in a different group of patients with a different profile of HLA types.
The differential diagnosis is against carcinomas, especially the cellular variant of anaplastic carcinoma and medullary
Tissue Tumour Online ;Cardiac Path Online
Copyright © 2020 histopathology-india.net