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Path Quiz Case- 74
Dr Sampurna Roy
MD
 Site created by Dr Sampurna Roy MD
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Benign sweat gland tumours Cysts: Hydrocystoma -Eccrine/Apocrine Porokeratotic eccrine ostial naevus Benign Neoplasms: Syringocystadenoma Papilliferum Chondroid Syringoma (benign mixed tumour) Low grade: Primary extramammary Paget’s disease Intermediate grade: Digital papillary adenocarcinoma High grade: |
| Sebaceous tumours |
| Melanocytic tumours |
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Interstitial Granulomatous Dermatitis |
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Eccrine syringofibroadenoma is a rare eccrine tumour first described by Mascaro in 1963. Clinical presentation: Solitary, often large nodular lesion. These are most often found in middle-aged and elderly patients. Site: Usually located on the extremities and rarely on the face. Microscopic features:
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Link1 Histologic examination reveal branching anastomosing strands of epithelial cells with ductal structures in a fibrovascular stroma. Epithelial strands are attached to the undersurface of the epidermis. The luminal cells show positive staining for carcinoembryonic antigen. A few cases with this pattern have been associated with carcinoma (syringofibrocarcinoma). Variant: The clear cell variant was reported by Fretzin in 1995. It is characterized by nests of periodic acid Schiff-positive clear cells resembling the clear-cell variant of syringoma. Multiple (palmoplantar) Eccrine syringofibroadenomas are a new cutaneous marker of the Schopf syndrome- (hidrocystomas of the eyelid, hypotrichosis- less than normal amount of hair on the head or body, hypodontia- fewer than the normal number of teeth, and nail abnormalities). Reactive Eccrine Syringofibroadenomatosis:- May occur next to various condition. Eg- Inflammatory dermatosis, bullous pemphigus, palmoplantar erosive lichen planus and chronic diabetic foot ulcers. |
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Histopathology-India.net diagnostichistopathology. blogspot.com Environmental Pathology Online
E-book - History of Medicine with special reference to India. |
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Myxoid
Tumours of Soft Tissue Classification of Soft Tissue Tumour Gross examination of soft tissue specimen A practical approach to histopathological reporting of soft tissue tumours Grading of soft tissue tumours Fibroblastic/ Myofibroblastic tumours |
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Cutaneous infection and infestations Histopathological patterns in cutaneous infections : Bacterial, Rickettsial and Chlamydial infection : Mycoses and algal infections |