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Pathology of Synovial Chondromatosis of Temporomandibular Joint

Dr Sampurna Roy MD

 

                                                                                                                      

 

Synovial chondromatosis is a benign monoarticular condition that rarely occurs in the temporomandibular joint. It mainly affects large joints such as knee, hip, shoulder, and elbow, commonly in male patients. However, its presentation in the temporomandibular joint, is a rare finding, occurring predominantly in females.

The etiology of this disease is unknown.

This benign synovial process is characterized by the formation of metaplastic cartilaginous nodes (loose bodies) inside connective tissue of articular surfaces.

The disease usually affects women who constitute almost 70% of reported cases and the age of the patient ranges between 18-75 years.

Pain and preauricular swelling are the most common presenting clinical complaints. 

The histological appearance is that of a benign chronic inflammation varying in severity and with metaplastic activity.

There are nodules of mature cartilage of varying cellularity within synovium and joint space.

The local clinical behavior, radiographic appearance, and histopathologic features can combine to create the appearance of a malignant lesion.

Differential diagnosis: Chondrosarcoma 

Complete removal of the loose bodies with excision of the affected synovium is the accepted treatment of synovial chondromatosis.

 

Further reading:

Synovial Chondromatosis of the Temporomandibular Joint Successfully Treated by Surgery.

Transforming growth factor beta 3 involved in the pathogenesis of synovial chondromatosis of temporomandibular joint.

Synovial chondromatosis of the temporomandibular joint.

Synovial chondromatosis of the temporomandibular joint: the effect of interleukin-1 on loose-body-derived cells.

Extra-articular synovial chondromatosis of the temporomandibular joint: pitfalls in diagnosis.

Synovial chondromatosis of the temporomandibular joint: clinical, surgical and histological aspects.

Synovial chondromatosis of the temporomandibular joint: clinical and immunohistopathological considerations.

The expression of fibroblast growth factor receptor-3 in synovial osteochondromatosis of the temporomandibular joint.  

Arthrocentesis in the treatment of loose bodies of the temporomandibular joint associated with synovial chondromatosis.

Synovial chondromatosis of the temporomandibular joint: a clinical, radiological and histological study.

The expression of fibroblast growth factor receptor-3 in synovial osteochondromatosis of the temporomandibular joint.

Synovial chondromatosis of the temporomandibular joint: report and analysis of eleven cases.

Synovial chondromatosis of the temporomandibular joint with extension to the middle cranial fossa.

Synovial chondromatosis of the temporomandibular joint with condylar extension.

 

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


 

 

 

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