 Site created by Dr Sampurna Roy MD
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Dr. Sampurna Roy MD
| Melanocytic Tumours |
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Melanocytic tumours 1. Acquired Melanocytic Naevus CLICK
Ancient Naevus CLICK
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Myxoid
Tumours of Soft Tissue Classification of Soft Tissue Tumour |
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This is a form of nevus which is usually
compound in type and consists of plump epithelioid cells and spindle
cells. The lesion has a wedge shaped contour and extends deep into the
dermis and may may even reach the subcutis. The melanocytes may display
irregular size and shape and the cells do not diminish in size at the
base of the lesion. The cells surround hair follicle, sweat glands and
nerves. Pilar muscles are some times infitrated. There is low mitotic
activity. No atypical mitotic figures are present. Clinically, this lesion usually occurs on the head and neck region and presents as darkly pigmented papule or nodule. Many authors regard this lesion as a variant of blue naevus. The relevant differential diagnosis include melanoma : 1.Melanoma of the thickness of deep penetrating naevus usually displays marked cellular and architectural atypia. 2. In deep penetrating naevus there is no pagetoid intraepidermal spread. 3. There is no irregular epidermal acanthosis or thinning 4. No irregular fibroinflammatory dermal response is seen in deep penetrating naevus. 5. Proliferating cell nuclear antigen (PCNA) is present in scattered melanocytes (less than 5%) in the deep penetrating nevus. In melanoma 25%-75% cells show immunopositivity with PCNA. IMAGE LINK (Dr.Weems) CASE LINKS: Case1 ; Case 2 |
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Abstracts: Deep penetrating nevus: a case report and brief literature review.Diagn Pathol.2006 Sep 25;1:31
Linear arrangement of multiple deep penetrating
nevi: report of first case and review of literature.Arch
Dermatol.2003 Dec;139(12):1608-10 Deep penetrating nevus.Am J Surg Pathol. 1989 Jan;13(1):39-44.
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Pigmented melanocytic lesions causing diagnostic
problems Prognostic parameters of melanoma Superficial spreading melanoma |
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Epidermal tumours:
Cutaneous Squamous Cell Carcinoma (Image &abstracts) Cutaneous infection and infestations |