Ectopic sebaceous glands
without attached hair follicle may be present near mucocutaneous
junction.
Clinical presentation:
The incidence of Fordyce's granules
increases from childhood to adulthood, and is slightly higher in men.
Presents as
tiny yellow papules.
Site:
Fordyce's Spots - Present along vermillion border of the lips or on the
oral mucosa.
Montgomery's tubercle-
Normal sebaceous
glands are distributed along a circle in the periphery of the areola of
the breast.
Ectopic sebaceous
glands are occasionally found in other sites - Eg:
Esophagus; penis; labia minora ; vagina
Normal sebaceous
glands on the vermilion border of the lips and the oral mucosa are
common in adults. Only pathologic sebaceous glands visible through the
epithelium should be regarded as Fordyce's granules.
Microscopic features: Image
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Histology shows a single sebaceous gland lesion consisting of single or
a group of small but mature sebaceous lobules around small sebaceous
duct extending to the surface epithelium. No associated hair follicles
are seen.
Image
Differential diagnosis:
Sebaceous hyperplasia (enlarged
sebaceous glands with numerous lobules around a centrally located wide
duct).
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