http://www.histopathology-india.net/SAClass.htm

Cysts:

Hydrocystoma -Eccrine/Apocrine

Hamartomas:

Eccrine/Apocrine naevus

Eccrine Angiomatous Hamartoma

Porokeratotic eccrine ostial naevus

Benign Neoplasms:

Syringocystadenoma Papilliferum

Hidradenoma Papilliferum

Nipple Adenoma

Syringoma

Spiradenoma

Cylindroma

Chondroid Syringoma (benign mixed tumour)

Poroma

Hidradenoma

Apocrine adenoma

Papillary eccrine adenoma

Syringofibroadenoma

Sebaceous hyperplasia is a common benign lesion of the sebaceous gland.

This lesion has been seen in heart transplant and bone marrow recipients & is probably due to the effects of Cyclosporine.

Clinical presentation:

Solitary or multiple  yellowish, umbilicated papules (1 to 3 mm in diameter) .

Usually occurs in middle aged patients , but cases have been reported in younger individuals.

Juxtaclavicular beaded line - variant of sebaceous hyperplasia characterized by papules arranged in parallel rows resembling 'strands of beads'.

Site:  Face, forehead, chest, areola, mouth, vulva etc.

Microscopic features:

Images: 1  2

Histology shows separate hyperplastic sebaceous glands ; mature sebaceous lobules connect to dilated central sebaceous duct ; essentially normal cytological appearance.

Lobules consist of :  (i) Basaloid or cuboidal cells without lipid droplets.  (ii) Layers of mature sebocytes with abundant lipid and scalloped nuclei.

Differential diagnosis:

Nevus sebaceus (lobules are aberrant, ducts open into the epidermis, there is epidermal hyperplasia and in some cases apocrine glands)

Rhinophyma (sebaceous glands are not as well defined and grouped as in sebaceous hyperplasia).

Sebaceous adenoma of oral cavity: report of case and comparative proliferation study with sebaceous gland hyperplasia and Fordyce's granules.Oral Dis 2003;9(6):323-7

Sebaceous gland hyperplasia of the vulva.Obstet Gynecol. 2002;99(5 Pt 2):919-21

Sebaceous hyperplasia: a clue to the diagnosis of dermatofibroma.J Am Acad Dermatol. 2001;44(1):94-5.

Sebaceous hyperplasia of the lower eyelid. Klin Monatsbl Augenheilkd. 1999;215(5):319-20.

Sebaceous gland hyperplasia as a side effect of cyclosporin A. Treatment with the CO2 laser.Dtsch Med Wochenschr. 1998;123(25-26):798-800.

Unilateral areolar sebaceous hyperplasia in a male.Am J Dermatopathol. 1996 Aug;18(4):417-9.

Sebaceous hyperplasia in organ transplant recipients: shared aspects of hyperplastic and dysplastic processes?J Am Acad Dermatol. 1996;35(5 Pt 1):696-9.

Diffuse sebaceous gland hyperplasia. A case report and an immunohistochemical study with cytokeratins.Am J Dermatopathol. 1996;18(3):296-301.

Areolar sebaceous hyperplasia: a case report.Cutis. 1996 Jul;58(1):63-4.

Intraoral sebaceous hyperplasia. Diagnostic criteria.Oral Surg Oral Med Oral Pathol. 1993;75(3):343-7.

Pathology of intraoral sebaceous glands.J Oral Pathol Med. 1993;22(6):241-5 

"Giant" senile sebaceous hyperplasia.J Dermatol.1992;19 (4): 238-41.

Giant solitary sebaceous gland hyperplasia clinically simulating epidermoid cyst.J Cutan Pathol.1988;15(6):396-8.

Sebaceous gland hyperplasia of the vulva: a case report.
Obstet Gynecol. 1986;68(3 Suppl):63S-65S.

Hyperplasia of sebaceous glands in a linear pattern of papules. Report of four cases.Am J Dermatopathol.1984;6 (3): 237-43.