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Surgical-Pathology.com
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Microvenular hemangioma is a rare, slowly growing, benign vascular tumour.
Clinical presentation: It usually presents as a solitary, asymptomatic, purple to red papule or plaque.
Age: Young to middle-aged adults.
Site: Extremities, particularly the forearms.
Microscopic features:
IMAGE LINKS (ESCOP): Image1 Image2 Image3 Image4 Image5
Histologically, these tumours are characterized by a proliferation of small-sized, irregularly branched venules with inconspicuous lumina.
The tumour has an infiltrative growth throughout the dermis The backround stroma is desmoplastic.
The flattened endothelial cells have oval to spindle-shaped nuclei and scant cytoplasm. The endothelial cells are surrounded by pericytes.
The tumour cells lack cellular atypia, pleomorphism, and mitotic figures.
Immunohistochemistry: Endothelial cells: FactorVIII- related antigen and CD34 positive. Pericytes: Smooth muscle actin positive.
Differential diagnosis: Early onset Kaposi's sarcoma- Eosinophilic globules are not present in microvenular hemangioma.
In the context of the histological similarity to a low-grade malignant tumour - early onset Kaposi's sarcoma, the awareness of microvenular hemangioma, a benign vascular tumour, is important.
 Site created by Dr Sampurna Roy MD
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Myxoid
Tumours of Soft Tissue Classification of Soft Tissue Tumour Gross examination of soft tissue specimen A practical approach to histopathological reporting of soft tissue tumours Grading of soft tissue tumours Fibroblastic/Myofibroblastic tumours |