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Acro-angiodermatitis / pseudo-Kaposi's sarcoma Reactive angioendotheliomatosis Targetoid hemosiderotic hemangioma Spindle cell hemangioma / hemangioendothelioma Kaposiform hemangioendothelioma Papillary intralymphatic angioendothelioma |
Microvenular hemangioma is a rare, slowly growing, benign vascular tumour.
Clinical presentation: It usually presents as a solitary, asymptomatic, purple to red papule or plaque.
Age: Young to middle-aged adults.
Site: Extremities, particularly the forearms.
Microscopic features:
IMAGE LINKS (ESCOP): Image1 Image2 Image3 Image4 Image5
Histologically, these tumours are characterized by a proliferation of small-sized, irregularly branched venules with inconspicuous lumina.
The tumour has an infiltrative growth throughout the dermis The backround stroma is desmoplastic.
The flattened endothelial cells have oval to spindle-shaped nuclei and scant cytoplasm. The endothelial cells are surrounded by pericytes.
The tumour cells lack cellular atypia, pleomorphism, and mitotic figures.
Immunohistochemistry: Endothelial cells: FactorVIII- related antigen and CD34 positive. Pericytes: Smooth muscle actin positive.
Differential diagnosis: Early onset Kaposi's sarcoma- Eosinophilic globules are not present in microvenular hemangioma.
In the context of the histological similarity to a low-grade malignant tumour - early onset Kaposi's sarcoma, the awareness of microvenular hemangioma, a benign vascular tumour, is important.
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Abstracts: Microvenular hemangioma.Ann Dermatol Venereol. 2004 ;131(5):475-7. Microvenular hemangioma in a boy with acute myelogenous leukemia.Pediatr Dermatol. 2003;20(3):266-7. Microvenular hemangioma.Dermatology. 2003;206(2):161-4. Microvenular hemangioma.Pathol Int. 1998;48(3):237-9. Microvenular hemangioma.Am J Dermatopathol. 1993 ;15(6) :534-8. Microvenular hemangioma.J Cutan Pathol. 1991;18(4):235-40.
PRIMARY TUMOURS OF THE HEART
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REPORTING OF CARDIAC TUMOURS
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Examination of pulmonary and pleural biopsies
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Percutaneous Needle
and Trucut Biopsy Specimen ;
Bronchial Biopsy Specimen
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Transbronchial Biopsy Specimen
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Transbronchial biopsy in lung transplant
recipients ;
Open lung biopsy
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Lobectomy and pneumectomy specimen
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Congenital Cystic Adenomatoid Malformation
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Acute Respiratory Distress Syndrome
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Sarcoidosis
; Bronchiolitis
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Emphysema
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Bronchial Asthma
;Chronic Bronchitis
Pulmonary
Alveolar Proteinosis
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Lipid Pneumonia ;
Pulmonary Hypertension
;Pulmonary edema
;Pulmonary Infection
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Pneumococcal Pneumonia
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Haemophilus influenza Infection ;
Klebsiella Pneumoniae
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Mycoplasma Pneumonia
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Pneumocystis Pneumonia
;
Legionellosis ;
Localized Fibrous Tumour of the Pleura
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Biphasic Epithelial/ Mesenchymal Lung Tumours
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Pulmonary
Carcinosarcoma
;Pulmonary Blastoma
;
Large Cell Neuroendocrine tumour; |
 Site created by Dr Sampurna Roy MD
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Myxoid
Tumours of Soft Tissue Classification of Soft Tissue Tumour Gross examination of soft tissue specimen A practical approach to histopathological reporting of soft tissue tumours Grading of soft tissue tumours Fibroblastic/Myofibroblastic tumours |
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Angiosarcoma
Dermatofibroma (aneurysmal variant) |