Dr Sampurna Roy
MD
 Site created by Dr Sampurna Roy MD
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Pathology of the Eyelid Inflammatory diseases of the Eyelid Tumour and tumour-like lesions of the Eyelid Epidermal tumours of the Eyelid |
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Granulomatous Reaction Pattern of the Skin
AnnularElastolytic Giant Cell Granuloma Skin lesion in Crohn's Disease |
Necrobiotic xanthogranuloma is a rare disorder which is frequently associated with paraproteinemia and lymphoproliferative diseases. Age: Middle-aged or elderly patients. Clinical presentation: Lesion presents as reddish, partly xanthomatous nodules or plaques. Site:
These are usually located around the periorbital area. Other sites
include extremities & trunk. Extensive areas of
hyaline necrobiosis surrounded by a palisade of histiocytes &
multinucleated giant cells ; Differential diagnosis: Necrobiosis Lipoidica: Much less collagen degeneration. Foam cells, large numbers of necrotic inflammatory cells & cholesterol clefts are absent . Atypical giant cells are not prominent. Panniculitis is localized to the septa . In necrobiotic xanthogranuloma the lobules are extensively involved. Necrobiosis lipoidica diabeticorum with cholesterol clefts in the differential diagnosis of necrobiotic xanthogranuloma.J Cutan Pathol. 1988 Feb;15(1):18-21. |
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Myxoid
Tumours of Soft Tissue Classification of Soft Tissue Tumour Gross examination of soft tissue specimen A practical approach to histopathological reporting of soft tissue tumours |