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Pathology of Cutaneous Sarcoidosis

Dr Sampurna Roy MD            

Dermatopathology Quiz Case No 63: 

Diagnosis: Cutaneous Sarcoidosis

 

                                                                                                                      

 

 

Skin sarcoidosis occurs in about 25% of patients with systemic disease and may also arise in isolation.

A wide range of clinical presentations of cutaneous sarcoidosis is recognised.

The diagnosis rests on the presence of non-caseating granulomas on skin biopsy and the exclusion of other granulomatous skin disease.

The treatment and overall prognosis of cutaneous sarcoidosis is primarily dependent on the degree of systemic involvement.

In patients with aggressive disease limited to the skin immunosuppressive therapy may be indicated.  

Microscopic Images of Cutaneous Sarcoidal Granulomas:

Image1

Image2

Related posts:  

Sarcoidosis ; Cutaneous Granulomatous Reaction Pattern.

 

Further reading:

The histologic spectrum of cutaneous sarcoidosis: a study of twenty-eight cases.

Comparison of cutaneous sarcoidosis with systemic sarcoidosis: a retrospective analysis

Verrucous cutaneous sarcoidosis: case report and review of this unusual variant of cutaneous sarcoidosis.

Adaptive Immune Responses in Primary Cutaneous Sarcoidosis

Diagnosis of cutaneous sarcoidosis; clinical and the prognostic significance of skin lesions

Granulomatous cutaneous sarcoidosis: diagnosis, relationship to systemic disease, prognosis and treatment.

Sarcoidosis can present with necrotizing granulomas histologically: two cases of ulcerated sarcoidosis and review of the literature.

Skin manifestations of sarcoidosis.

Clinical spectrum and histological analysis of 32 cases of specific cutaneous sarcoidosis.

 

 

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


 

 

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