Tissue Tumour Online
Pathology of Angiolipoma
Occurs in young adults
Site: These subcutaneous tumours are usually located on the forearm, arm and chest wall.
Clinical presentation: Presents as multiple, painful yellow, firm, circumscribed tumours.
Angiolipoma usually do not recur after excision. New lesions may continue to develop elsewhere.
Microscopic Images of Angiolipoma
-Thin fibrous capsule with fibrous septa dividing the lesion into lobules.
-There are mature adipocytes together with groups of small vessels.
- Presence of fibrinous microthrombi in the lumen is a diagnostic feature.
- In 'cellular angiolipoma' the vascular component is more than 90%.
- Prominent pericytes may be present around the capillaries.
- Numerous mast cells are noted throughout the tumour.
- Degenerative changes (i.e. hyalinization, myxoid change and fibrosis) may be present in longstanding cases.
One must exclude well-differentiated angiosarcoma of the breast from angiolipomas arising on the chest wall.
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