DermPath-India

     Site created by

 Dr Sampurna Roy MD

          

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               Desmoplastic/Spindle cell
/Neurotropic Melanoma

       Dr. Sampurna Roy  MD

 
  Gastrointestinal Stromal Tumour

      

http://www.histopathology-india.MelanocyticTumours.htm

June 2009
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Melanocytic tumours
              
1. Acquired Melanocytic Naevus

Ancient Naevus 
Halo naevus
Balloon cell naevus 
Combined Naevus 
Recurrent melanocytic naevus 
                   
2. Spindle and epithelioid cell naevi

Spitz naevus 
Pigmented spindle cell naevus 

        

DermAtlas- Image:  Links1   2   3   4

This lesion is characterised  by a combination of common acquired naevus or Spitz naevus with blue naevus  or congenital naevus. Histologically the two lesions are usually  present in distinct areas or may be closely intermingled.

Clinically, combined naevi present as  well circumscribed hyperpigmented spots surrounded by less pigmented areas. 

These lesions may simulate melanoma by being asymmetrical and displaying markedly irregular pigmentation. 

Histopathology, one variant reveals epithelioid and spindle cells of Spitz naevus together with dysplastic naevus.  In another variant there are small melanocytes with large balloon cells, simulating balloon cell melanoma.  It is not at all uncommon to see a very small  component of non-blue naevus in a cellular blue naevus or deep penetrating naevus.

Unlike melanoma, there is no evidence pagetoid intraepidermal spread.

Image Link1  ; Image Link 2
 

                    

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Pigmented melanocytic lesions causing diagnostic problems

Prognostic parameters of melanoma

Lentigo maligna melanoma

Superficial spreading melanoma

Nodular melanoma

Acral lentiginous melanoma

Desmoplastic /Spindle cell /
Neurotropic melanoma

Naevoid melanoma

Balloon cell melanoma

Annular Elastolytic Giant Cell Granuloma

Skin lesion in Crohn's Disease

Blastomycosis-like pyoderma

Foreign body granuloma

Rosacea

Interstitial Granulomatous Dermatitis


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