DermPath-India

     Site created by

 Dr Sampurna Roy MD

          

http://www.histopathology-india.net/dermpath.htm

              HISTOPATHOLOGY INDIA.COM

             Desmoplastic/Spindle cell
/Neurotropic Melanoma

       Dr. Sampurna Roy  MD

 
Web www.histopathology-india.net
  Gastrointestinal Stromal Tumour

      

http://www.histopathology-india.MelanocyticTumours.htm

May 2007

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INDEX: A-D ; INDEX: E-L ;INDEX: M-P ;INDEX: Q-Z ; FUNGAL DISEASE ; VIRAL DISEASE.

Melanocytic tumours
              
1. Acquired Melanocytic Naevus

Ancient Naevus  
Halo naevus
Balloon cell naevus
Combined Naevus
Recurrent melanocytic naevus

                   
2. Spindle and epithelioid cell naevi

Spitz naevus
Pigmented spindle cell naevus

3. Blue naevi

Common blue naevus 
Cellular blue naevus


4. Dermal melanocytoses

Naevus of Ota

Naevus of Ito  
Mongolian spot  

5. Congenital melanocytic naevi

6. Dysplastic melanocytic naevi                                           

        
This lesion is characterised  by a combination of common acquired naevus or Spitz naevus with blue naevus  or congenital naevus. Histologically the two lesions are usually  present in distinct areas or may be closely intermingled.

Clinically, combined naevi present as  well circumscribed hyperpigmented spots surrounded by less pigmented areas. 

These lesions may simulate melanoma by being asymmetrical and displaying markedly irregular pigmentation. 

Histopathology, one variant reveals epithelioid and spindle cells of Spitz naevus together with dysplastic naevus.  In another variant there are small melanocytes with large balloon cells, simulating balloon cell melanoma.  It is not at all uncommon to see a very small  component of non-blue naevus in a cellular blue naevus or deep penetrating naevus.

Unlike melanoma, there is no evidence pagetoid intraepidermal spread.           Image Link1  ;   Image Link 2
 

                    

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Pigmented melanocytic lesions causing diagnostic problems

Prognostic parameters of melanoma

Lentigo maligna melanoma

Superficial spreading melanoma

Nodular melanoma

Acral lentiginous melanoma

Desmoplastic /Spindle cell /
Neurotropic melanoma

Naevoid melanoma

Balloon cell melanoma