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Path Quiz Case- 26
Dr Sampurna Roy
MD
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Benign sweat gland tumours Cysts: Hydrocystoma -Eccrine/Apocrine Porokeratotic eccrine ostial naevus Benign Neoplasms: Syringocystadenoma Papilliferum Chondroid Syringoma (benign mixed tumour) Low grade: Primary extramammary Paget’s disease Intermediate grade: Digital papillary adenocarcinoma High grade: |
| Sebaceous tumours |
This benign tumour was previously regarded as an apocrine tumour . According to some authors this tumour is a variant of apocrine adenoma with specific features. Now there is increasing evidence to suggest that it is closely related to the recently described mammary-like anogenital glands. Site: Almost always located in the vulval or perianal regions. Ectopic lesions have been reported on the face, scalp, eyelid, auditory canal and arm. Clinical presentation: The tumour usually occurs in middle aged women as small nodules (1cm or less in size). Microscopic features:
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Link1 Histologically, these are circumscribed solid or partly cystic tumour containing papillary and glandular areas. There are two types of epithelium - tall columnar cells with pale eosinophilic cytoplasm and underlying myoepithelial cell layer. Prominent apocrine changes are noted in areas. Mitotic count is occasionally high. PAS positive diastase-resistant granules are present in the apices of the large cells. The differential diagnosis includes adenocarcinoma. |
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Surgical-Pathology.com
Environmental Pathology Online
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Tumours of the Hair Follicle Hair Germ Differentiation: Desmoplastic Trichoepithelioma
Cutaneous lymphadenoma Tumour of Follicular Infundibulum Outer root
sheath differentiation: Proliferating Trichilemmal Cyst (Pilar Tumour)
Matrical differentiation: |