Glossary   

Gross examination of the skin specimen

Reporting of biopsies taken for Inflammatory Skin Diseases

Lichenoid (Interface)Tissue Reaction Pattern

Psoriasiform Reaction Pattern

Vesiculobullous Reaction Pattern

Spongiform Reaction Pattern

Vasculopathic Reaction Pattern

Lichen planus-like lesions

Bullous Pemphigoid

Dermatitis Herpetiformis

Hailey-Hailey Disease

Erythema Nodosum

Folliculitis

Impetigo

Furuncle(Boil)

Carbuncle

Toxic Shock Syndrome

Drug related cutaneous lesions

Cutaneous lesion in graft-
versus host disease

Granuloma Annulare

Necrobiosis Lipoidica

Necrobiotic Xanthogranuloma   

Rheumatoid Nodule

Lupus Vulgaris

Cutaneous Sarcoidosis

Melkersson Rosenthal Syndrome

Annular Elastolytic Giant Cell Granuloma

Skin lesion in Crohn's Disease

Blastomycosis-like pyoderma

Foreign body granuloma

Rosacea

Interstitial Granulomatous Dermatitis

Interstitial Granulomatous Drug Reaction

Granulomatous T-cell lymphoma

Histopathological patterns in cutaneous infections

1: Bacterial, Rickettsial and Chlamydial infection

2 : Spirochetal Infection

3 : Mycoses and algal infections

4 : Protozoal Infections

5 : Helminth Infections

6 : Viral Infections

Cutaneous lesion associated
with AIDS

Acquired Melanocytic Naevus

Ancient Naevus

Halo naevus

Balloon cell naevus

Mongolian Spots /Ota's naevus /Ito's naevus

Blue naevus-variants

Deep penetrating naevus  

Combined Naevus

Recurrent naevus

Spitz naevus

Dysplastic naevus

Congenital naevus

Spindle cell naevus

Pigmented melanocytic lesions causing diagnostic problems

Prognostic parameters of melanoma

Lentigo maligna melanoma

Superficial spreading melanoma

Nodular melanoma

Acral lentiginous melanoma

Desmoplastic /Spindle cell /Neurotropic  melanoma

Naevoid melanoma

Balloon cell melanoma

Epidermal tumours

Epidermal Naevus

Prurigo Nodularis

Acanthomas

Clear cell acanthoma

Large cell acanthoma

Warty Dyskeratoma

Seborrheic Keratosis

Verruca vulgaris;

Keratoacanthoma

Actinic Keratosis

Bowen's disease

Basal Cell Carcinoma

Squamous Cell Carcinoma

Visit: Dermatopathology Case 30 ; Xanthelasma ; Gastric Xanthoma

Human papillomavirus has been indicated in several cases of VX as a causative agent. Cases have been reported in immunocompromised patients with HIV-1 infection and graft versus host disease.

VX may be associated with epidermal nevi, fibroepithelial polyp of the vulva, squamous cell carcinoma, arteriovenous hemangioma, discoid lupus erythematosus and lymphedema of the leg.

Site:  Predominantly noted in the oral cavity, but it has been reported to occur on the genital skin and mucosa (vulva, perianal skin, scrotum, penis).

Gross:  Usually solitary, flat plaques or warty lesions (about 2 cm in diameter).

Microscopic features:  Image Link1 ; Image Link2 ; Image Link3; Image Link4.

Hyperkeratosis, focal parakeratosis & verrucous acanthosis.

Exocytosis of neutrophils into the upper layer of epithelium and the parakeratotic scales.

Characteristic feature:  Presence of numerous xanthoma cells in the papillary dermis. Cells contain lipid and small amounts of PAS-positive diastase resistant material.

Immunohistochemistry :

 The characteristic foam cells of verruciform xanthoma showed strong positive staining for CD 68[KP1] and vimentin & weak positivty for cytokeratin. S100 protein is negative.

Verruciform xanthoma of the oral cavity: clinicopathological study relating to pathogenesis. Report of three cases.APMIS. 2005 Sep;113(9):629-34.

Verruciform xanthoma in close association with isolated epidermolytic acanthoma: a case report and review of the Japanese dermatological literature.J Dermatol. 2005 Jun;32(6):464-8.

Study of the clinicopathology on verruciform xanthoma of the oral cavity. Shanghai Kou Qiang Yi Xue. 2005 Aug;14(4):370-3.

Recurrent verruciform xanthoma of the vulva. Int J Gynecol Pathol. 2004 Jan;23(1):75-7.

Verruciform xanthoma. Mund Kiefer Gesichtschir. 2003 Jan;7(1):52-5.

Verruciform xanthoma--biological profile of 282 oral lesions based on a literature survey with nine new cases from Japan.Oral Oncol. 2003 Jun;39(4):325-36.

Verruciform xanthoma of the esophagus. Hum Pathol. 2003 Aug;34(8):814-5.

A giant verruciform xanthoma. J Cutan Pathol. 2002 Feb;29(2):119-24.

Verruciform xanthoma of the oral mucosa. Report of four cases and a review of the literature.Oral Oncol. 2001 Apr;37(3):326-31.

Association of human papillomavirus type 6 with a verruciform xanthoma. Am J Dermatopathol. 2000 Oct;22(5):447-52.

Verruciform xanthoma and concomitant lichen planus of the oral mucosa. A report of three cases.Int J Oral Maxillofac Surg. 1999 Feb;28(1):62-6.

Cutaneous verruciform xanthoma: a report of five cases investigating the etiology and nature of xanthomatous cells.Am J Surg Pathol. 1998 Apr;22(4):479-87.

Verruciform xanthoma of the oral mucosa: an immunohistochemical and ultrastructural study of two cases.Oral Oncol 1997 Jul; 33(4): 279-83

Verruciform xanthoma of the penis.Actas Urol Esp. 1997 Sep;21(8):797-9.

Squamous cell carcinoma associated with verruciform xanthoma of the penis. Am J Dermatopathol. 1996 Oct;18(5):551-4.

Verruciform xanthoma of the penis with acantholytic cells.Clin Exp Dermatol. 1995 Nov;20(6):504-8.

Verruciform xanthoma: a benign penile growth.J Urol. 1995 May;153(5):1625-7.

Verruciform xanthoma in a bone marrow transplant recipient.Oral Surg Oral Med Oral Pathol. 1993;75(5):591-4.

Multifocal verruciform xanthoma of the upper aerodigestive tract in a child with a systemic lipid storage disease. Am J Surg Pathol.1989 Apr;13(4):309-16.

Verruciform xanthoma of the vulva: case report.Genitourin Med. 1989 Aug;65(4):252-4.

Verruciform xanthoma within carcinoma in situ.J Oral Maxillofac Surg. 1989 Apr;47(4):398-400.

Langerhans cells in verruciform xanthomas: an immunoperoxidase study of 10 oral cases. J Oral Pathol. 1986 Jan;15(1):48-53.

Verruciform xanthoma of the vulva. Report of two cases.Am J Clin Pathol. 1979 Feb;71(2):224-8.

Verruciform xanthoma. Further light and electron microscopic studies, with the addition of a third case.Oral Surg Oral Med Oral Pathol. 1975 Aug;40(2):246-56.