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 Dr Sampurna Roy MD

http://www.histopathology-india.net/dermpath.htm

                           

       Dr  Sampurna Roy  MD

Syn:  Endemic Syphilis ; Nonvenereal Syphilis

Bejel is a syphilis-like disease transmitted by a non-venereal route, such as from an infected baby to the breast of its mother, from mouth to mouth, or from utensils to mouth.  Visit:  Pathology of Syphilis ; Neurosyphilis; Congenital Syphilis ;  Yaws .

Bejel is caused by a spirochete, Treponema pallidum var. endemic.

Poor children who live in rural arid areas under unsanitary conditions are commonly affected.

Other than on the nursing breast, primary lesions are rare.

Secondary lesions in the mouth are identical to the mucous lesions of venereal syphilis and may spread from the upper airway to the larynx. 

Lesions of perineum and bone and gummas of the breast occur, but cardiovascular and neurologic lesions and congenital transmission are rare.

Numerous spirochetes are present in the epidermis, neutrophils invade the skin, plasma cells are prominent in the dermis, and there is a syphilitic vasculitis.

Serologic tests for syphilis are positive, but the clinical presentation is different. Penicillin is an effective remedy.

 Abstracts:

Bejel: Acquirable only in childhood?Acta Trop. 2006 Oct 16

Overview of endemic treponematoses.Med Trop (Mars). 2006 Feb;66(1):15-20

Bejel in Malatya, Turkey.J Trop Pediatr. 1995;41(2):117-20

Treponemal disease revisited: skeletal discriminators for yaws, bejel, and venereal syphilis.Clin Infect Dis. 1995 May;20(5):1402-8

Ocular manifestations of endemic syphilis (bejel). Ophthalmology. 1989 Jul;96(7):1087-91

Review:endemic treponematoses are not always eradicated. Med Trop (Mars). 1989 Jul-Sep;49(3):237-44