Skin Appendage Tmour

            

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 Microcystic Adnexal Carcinoma

       Dr  Sampurna Roy  MD

 
     DermPath-India

     Site created by

 Dr Sampurna Roy MD

          

http://www.histopathology-india.net/dermpath.htm

February 2008 

Soft TissueTumours of Uncertain Differentiation               

Notochordal Tumour - Chordoma

Extra-adrenal Paraganglioma

Gastrointestinal Stromal Tumour

Benign sweat gland tumours

Cysts:

Hydrocystoma -Eccrine/Apocrine

Hamartomas:

Eccrine/Apocrine naevus

Eccrine Angiomatous Hamartoma

Porokeratotic eccrine ostial naevus

Benign Neoplasms:

Syringocystadenoma Papilliferum

Hidradenoma Papilliferum

Nipple Adenoma

Syringoma

Spiradenoma

Cylindroma

Chondroid Syringoma (benign mixed tumour)

Poroma

Hidradenoma

Apocrine adenoma

Papillary eccrine adenoma

Syringofibroadenoma

Malignant sweat gland tumour 

Low grade:

Microcystic adnexal carcinoma

Eccrine epithelioma

Adenoid cystic carcinoma

Mucinous carcinoma

Primary extramammary Paget’s disease

Intermediate grade:

Porocarcinoma

Digital papillary adenocarcinoma

High grade:

Hidradenocarcinoma

Apocrine adenocarcinoma

Eccrine ductal carcinoma

Spiradenocarcinoma

Malignant cylindroma

Sebaceous tumours

Fordyce's Spots

Steatocystoma

Nevus Sebaceous

Folliculosebaceous Cystic Hamartoma

Sebaceous Hyperplasia

Sebaceoma

Sebaceous Adenoma

Sebaceous Carcinoma

                        

Apocrine adenomas are very rare adnexal tumours.

Tubular apocrine adenoma (tubulopapillary hidradenoma with apocrine differentiation) was first described in 1972.  Visit:Papillary Eccrine Adenoma

Tubular apocrine adenomas show some features of syringocystadenoma papilliferum . Some cases have been associated with naevus sebaceous.

Clinical presentation: Slow growing circumscribed nodule.

Site:  Apocrine adenomas have been reported in the axilla, cheek and breast. Cases reported in vulval and perianal region are now known as 'adenomas of anogenital mammary-like glands'. Tubular apocrine adenomas are often located on the scalp.

Microscopic features:

Tumour is composed of well-differentiated dilated tubular structures situated in the dermis and sometimes in the subcutis ;  Tubules contain typical apocrine epithelial cells, some with hyaline or clear cell differentiation ; Myoepithelial cells are also present (absent in adenocarcinoma) ; Papillary projections and cystic changes may be present ; Overlying epidermis may be hyperplastic ;  Tubules are separated by fibrous tissue with scanty inflammatory cells.

Differential diagnosis:  Syringocystadenoma Papilliferum ;  Apocrine adenocarcinoma;

          Image Link (Dr.Weems): Image1 ; Image2 
         
DermAtlas: Related link

                   

Abstract:

Tubular apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal.J Laryngol Otol. 2005;119(12):1004-6.

Mixed tubulopapillary hidradenoma and syringocystadenoma papilliferum occurring as a verrucous tumor.J Cutan Pathol. 2003 ;30(3):206-10.

Tubular apocrine adenoma in association with syringocystadenoma papilliferum.Dermatol Online J. 2003  ;9(1):7.

Is tubular apocrine adenoma a distinct clinical entity?
Am J Dermatopathol. 1993;15(5):482-7.

A case of tubular apocrine adenoma with syringocystadenoma papilliferum.J Cutan Pathol. 1989;16(4) :230-6.

Tubular apocrine adenoma.J Cutan Pathol. 1987;14(2):114-7.

Tubular apocrine adenoma: apropos of a case. Dermatologica. 1984;169(1):23-8.

Tubular apocrine adenoma.J Cutan Pathol. 1976;3(2):75-87.   

 

Tumours of the Hair Follicle

Hair Germ Differentiation:

Trichoepithelioma  ; Desmoplastic Trichoepithelioma  ; Trichofolliculoma ;

Trichoblastoma ; Cutaneous lymphadenoma ;

                          
    
Infundibular differentiation:

Trichoadenoma ; Dilated Pore of Winer ; Pilar Sheath Acanthoma ;

Tumour of Follicular Infundibulum ;

Outer root sheath differentiation:
                    
Trichilemmoma ; Trichilemmal Carcinoma ; Proliferating Trichilemmal Cyst (Pilar Tumour) ;

Matrical differentiation:Pilomatrixoma and Pilomatrix Carcinoma .

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Soft Tissue Pathology

Case Index

Infectious Disease Online; INDEX: A-D ; INDEX: E-L ; INDEX: M-P INDEX: Q-Z ; FUNGAL DISEASE ; VIRAL DISEASE.

Myxoid Tumours of Soft Tissue

Classification of Soft Tissue Tumour

Gross examination of soft tissue specimen          

A practical approach to histopathological reporting of soft tissue tumours

Grading of soft tissue tumours

Lipomatous tumours

Neural tumours

Myogenic tumours

Fibroblastic/Myofibroblastic tumours

Myofibroblastic tumours

Fibrohistiocytic tumours

ChondroOsseous tumours


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