Apocrine adenomas are
very rare adnexal tumours.
Tubular apocrine adenoma
(tubulopapillary hidradenoma with apocrine differentiation) was first
described in 1972. Visit:Papillary Eccrine Adenoma
Tubular apocrine
adenomas show some features of
syringocystadenoma papilliferum . Some
cases have been associated with
naevus sebaceous.
Clinical presentation:
Slow growing circumscribed nodule.
Site:
Apocrine adenomas have been
reported in the axilla, cheek and
breast. Cases reported in vulval and perianal region are now known as
'adenomas of anogenital mammary-like glands'. Tubular apocrine
adenomas are often located on the scalp.
Microscopic features:
Tumour is composed of well-differentiated dilated
tubular structures situated in the dermis and sometimes in the subcutis ;
Tubules contain typical apocrine
epithelial cells, some with hyaline or clear cell differentiation ; Myoepithelial cells are also present (absent in adenocarcinoma)
; Papillary projections and cystic changes may be present ; Overlying epidermis may be hyperplastic
; Tubules
are separated by fibrous tissue with scanty inflammatory cells.
Differential diagnosis: Syringocystadenoma Papilliferum
;
Apocrine adenocarcinoma;
Image
Link (Dr.Weems):
Image1 ;
Image2
DermAtlas:
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