Dr  Sampurna Roy  MD

Argentine hemorrhagic fever (AHF) is a viral disease caused by Junin virus and characterized by hematologic and neurological involvement. (Arenaviruses include Junin virus, Lassa virus, Machupo virus, Guanarito virus and Sabia).

 Visit: Arenavirus  ;  Lassa Fever   ; Viral hemorrhagic fevers

It is a severe illness whose symptoms resemble those of Korean Hemorrhagic Fever .

An epidemic developed in rural agricultural areas and villages northwest of Buenos Aires in 1958.

The virus is found naturally in wild in wild rodents and may be transmitted in food or contaminated airborne dust.

The main hematologic features are leukopenia, thrombocytopenia, and bone marrow hypoplasia.

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Immune response to vaccination against Argentine hemorrhagic Fever in an area where different arenaviruses coexist.Viral Immunol. 2006 Summer;19(2):196-201.

Characterization of the cellular receptors for the South American hemorrhagic fever viruses Junin, Guanarito, and Machupo.Virology. 2006 Jun 5;349(2):476-91. Epub 2006 Mar 30

Inhibition of cell fusion in Junin virus-infected cells by sera from Argentine hemorrhagic fever patients.J Clin Virol. 2005 Apr;32(4):286-8.

Viral hemorrhagic fevers of South America.Biomedica.2002;22(3):287-95

Relationship between hematopoietic growth factors levels and hematological parameters in Argentine hemorrhagic fever.Am J Hematol. 2000 May;64(1):1-6.

Clinical case definitions for Argentine hemorrhagic fever.Clin Infect Dis. 1999 May;28(5):1091-4