DermPath-India

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 Dr Sampurna Roy MD

          

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           Desmoplastic/Spindle cell
/Neurotropic Melanoma

    Dr. Sampurna Roy  MD

 
    Gastrointestinal Stromal Tumour

    

http://www.histopathology-india.MelanocyticTumours.htm

May 2009
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Melanocytic tumours
              
1. Acquired Melanocytic Naevus

Ancient Naevus  
Halo naevus
Balloon cell naevus  
Combined Naevus
Recurrent melanocytic naevus

                   
2. Spindle and epithelioid cell naevi

Spitz naevus
Pigmented spindle cell naevus

3. Blue naevi

Common blue naevus 
Cellular blue naevus


4. Dermal melanocytoses

Naevus of Ota

Naevus of Ito  
Mongolian spot  

5. Congenital melanocytic naevi                                              
6. Dysplastic melanocytic naevi

Pathology of the Eyelid

Inflammatory diseases of the Eyelid

Tumour and tumour-like lesions of the Eyelid

Adnexal Tumours of the eyelid

Epidermal tumours of the Eyelid

Mesenchymal Tumours of the Eyelid

Melanocytic tumours of the Eyelid

             
The tumour should contain more than 50% balloon cells. There are distinct areas of characteristic melanoma cells and prominent mitoses. Occasional intraepidermal pagetoid spread may be present.

The main differential diagnosis  is balloon cell naevus. The cytoplasmic features of the balloon cells observed in balloon cell melanoma resemble those noticed in balloon cell naevus, but the presence of nuclear pleomorphism, atypia, and mitoses and the absence of intervening stroma help distinguish balloon cell melanoma.

Microscopically, balloon cell melanoma also must be differentiated from other clear cell tumours such as clear cell sarcoma (malignant melanoma of soft parts), hibernoma, xanthelasma , sebaceous neoplasms, metastatic renal cell carcinoma, porocacinoma, (malignant) granular cell tumour, granular (clear) cell basal cell carcinoma, clear cell syringoma, and atypical fibroxanthoma.

Visit: Clear cell carcinoma of skin

                                
 
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Abstract:

Metastatic balloon cell melanoma: a case report.Acta Cytol. 2005 Sep-Oct;49(5):543-8.

Epidermotropic xanthoma mimicking balloon cell melanoma.Am J Dermatopathol. 2000 Apr;22(2):176-8.

Glycogen-rich malignant melanomas and glycogen-rich balloon cell malignant melanomas: frequency and pattern of PAS positivity in primary and metastatic melanomas.Arch Pathol Lab Med. 1998 Apr;122(4):353-60.

Balloon-cell nevi and balloon-cell malignant melanoma.Arkh Patol. 1996 Jul-Aug;58(4):64-7.

Balloon cell malignant melanoma of the skin. A clinicopathologic study of 34 cases with  histochemical, immunohistochemical  and ultrastructural  observations. Cancer 1992; 69; 2942-2952

Balloon cell melanoma: a report of two cases.J Cutan Pathol. 1988 Aug;15(4):230-3.

Balloon cell malignant melanoma. J Am Acad Dermatol 1985; 13: 351-354

                             


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Soft Tissue Pathology;

Myxoid Tumours of Soft Tissue Classification of Soft Tissue Tumour;  Gross examination of soft tissue specimen ;  A practical approach to histopathological reporting of soft tissue tumours Grading of soft tissue tumours ; Lipomatous tumours ;Neural tumours ; Myogenic tumours ;Vascular tumours ;Fibroblastic/Myofibroblastic tumours ; Myofibroblastic tumours ;  Fibrohistiocytic tumours ; ChondroOsseous tumours ; Soft TissueTumours of Uncertain Differentiation ; Notochordal Tumour -Chordoma ;Extra-adrenal Paraganglioma ; Gastrointestinal Stromal Tumour ;

 

Pigmented melanocytic lesions causing diagnostic problems

Prognostic parameters of melanoma

Lentigo maligna melanoma

Superficial spreading melanoma

Nodular melanoma

Acral lentiginous melanoma

Desmoplastic /Spindle cell /
Neurotropic melanoma

Naevoid melanoma

Balloon cell melanoma

Granulomatous Reaction Pattern of the Skin

Granuloma Annulare

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Skin lesion in Crohn's Disease

Blastomycosis-like pyoderma

Foreign body granuloma

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Granulomatous T-cell lymphoma


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